I’ve only been using hugin for an hour now, and I’m really impressed.
The mac binary doesn’t include the ability to automatically determine how images overlap, but it’s pretty easy to make that work, too.
First download the hugin binary. The Mac OS X port is here.
Then install the autopano binary.
First install MacPorts.
Then run:
sudo port selfupdate sudo port install autopano-sift-c
I had a problem with cmake hanging during install. If port stalls for you, ctrl-c, then sudo port clean cmake ; sudo port install cmake ; sudo port install autopano-sift-c again.
Then tell Hugin where the binary is. Go to Hugin > Preferences… and click the “Autopano” tab, and make it look like this:

Close the preferences window, and the next time you use the “Assistant” tab and load images, you’ll see that the alignment is done for you automatically.
Here’s an example taken from Bryce Point in Bryce Canyon:
(it’s also one of the banners).